Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage
Protandim Nrf2 Synergizer by LifeVantage

Protandim Nrf2 Synergizer by LifeVantage

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A Science-Based, Patented, Herbal Blend

     Protandim Nrf2, "The Little Yellow Pill", works to activate the Nrf2 pathway; a very necessary component in humans and animals designed to combat the damaging effects of cellular stress, disease and aging. The Nrf2 pathway is recognized as perhaps the body's most important cellular defense mechanism. 

     Protandim Nrf2 Synergizer is the only supplement shown to reduce oxidative stress by 40% in just 30 days. This finding is backed by over 30 independent studies conducted by institutions such as Harvard, Ohio State, and the American Journal of Physiology, among others.

What's Inside?

  • Turmeric Root

    Used for 4,000 years in both Ayurvedic and Chinese cultures and shown to help fight cellular stress, maintain joint health, and aid digestion.*

  • Green Tea

    Contains high concentration of powerful antioxidants and known to support healthy mental processes and cardiovascular health.*

  • Bacopa

    Known to promote cognitive abilities, concentration, and alertness, and studies suggest it provides strong cellular defense.*

  • Milk Thistle

    Used for 2,000 years to support liver, kidney, and gallbladder function, and studies suggest it supports healthy detoxification.*

  • Ashwagandha

    The “king of Ayurvedic herbs,” an adaptogen with multiple benefits, including support for memory enhancement and restful sleep.*

The raw ingredients are verified, carefully weighed out, blended and pressed into tablet form following strict Good Manufacturing Practices (GMP) guidelines. Every lot of finished Protandim Nrf2 Synergizer is tested for compliance to approved specifications in addition to receiving a final quality inspection following dietary supplement regulations. Every lot must, again, meet or exceed established finished product specifications before it can be released by LifeVantage Quality Assurance. 

About Nrf2 Activation

Nrf2 is a powerful protein that is latent within each cell in the body, unable to move or operate until it is released by an Nrf2 activator. Once released it migrates into the cell nucleus and bonds to the DNA at the location of the Antioxidant Response Element (ARE) or also called hARE (Human Antioxidant Response Element) which is the master regulator of the total antioxidant system that is available in ALL human cells.

This balancing act becomes disrupted as one ages, or when the body is overcome by toxicity, malnutrition, malfunction and disease resulting in further cellular damage. This damage is known as oxidative stress and is accompanied by free radical production. Oxidative stress (and the associated free radical damage) contribute to the progression of hundreds of health conditions, aging and disease symptoms.

Direct Antioxidants, One-to-One Ratio

Direct antioxidants such as vitamin C, Vitamin E, berries and juices are often used to neutralize free radicals and prevent damage the free radicals cause. One molecule of antioxidants from these sources neutralizes one free radical, i.e. they combat free radicals on a one-to-one ratio. However, there comes a tipping point where the direct antioxidants are inadequate enough to take care of all the damage.

Nrf2, One-to-One Million Ratio

A more powerful approach to fighting free radicals is to use the body’s own self defense mechanism. When Nrf2 is activated inside the nucleus, it turns on the production of antioxidant enzymes such as Catalase, Glutathione Peroxidase and Superoxide Dismutase (SOD). These antioxidant enzymes are powerful enough to neutralize up to one million free radicals! This million-to-one ratio proves to be a much more effective approach in combating aging and disease conditions than the one-to-one ratio.

Are You Ready to Get Activated or Activate Your Animals?

To shop LifeVantage products including Protandim Nrf2 (for humans & horses), Petandim (for dogs), Tri-Synergizer & more: 👉 Place My Order!


Why Take Antioxidants When Your Body Can Make Them?

  • Reduces oxidative stress by 40% in just 30 days
  • Produces enzymes capable of neutralizing more than 1,000,000 free radicals
  • Significantly reduces cellular stress
  • Supports the body's natural ability to repair and rejuvenate its own cells
  • Helps the body detoxify genes, keeping the master blueprint of the cell’s function intact
  • Helps to regulate survival genes
  • Supports normal metabolic function

  • Helps body adapt to physical and mental stressors

  • Helps maintain normal vitality/energy

  • Helps support/maintain healthy immune function

  • Helps relieve stress and anxiety

The following is a list of diseases and/or disorders that are directly linked to high oxidative stress and, as a result, NRF2 may help improve. These only represent a fraction of the hundreds of conditions caused by an excess of free radical production:

Metabolic Disorders, Cardiovascular, Respiratory, Ophthalmology, Gastrointestinal, Toxicology, Genetic Disorders, Genito Urinary System And Sex Hormones, Infectious Disease and Musculoskeletal Disorders which include indications Inflammation, Multiple Sclerosis, Chronic Obstructive Pulmonary Disease (COPD), Diabetic Nephropathy, Psoriasis, Type 2 Diabetes, Amyotrophic Lateral Sclerosis, Cardiomyopathy, Diabetic Complications, Friedreich Ataxia, Parkinson\’s Disease, Pulmonary Arterial Hypertension, Systemic Sclerosis (Scleroderma), Type 1 Diabetes (Juvenile Diabetes), Age Related Macular Degeneration, AIDS Associated Dementia, Alport Syndrome, Alzheimer\’s Disease, Aspiration Pneumonitis, Asthma, Atherosclerosis, Autism, Brain Ischemia, Breast Cancer, Cardiovascular Disease, Cerebral Vasospasm, Chagas Disease (American Trypanosomiasis), Chronic Kidney Disease (Chronic Renal Failure), Encephalomyelitis, Fibromyalgia, Focal Segmental Glomerulosclerosis (FSGS), Huntington Disease, Idiopathic Pulmonary Fibrosis, Idiopathic Pulmonary Hypertension, Ischemia Reperfusion Injury, Ischemic Stroke, Medulloblastoma, Metastatic Breast Cancer, Metastatic Melanoma, Mitochondrial Diseases, Nephropathy, Neuro Muscular Disorders, Neuroblastoma, Neurodegenerative Diseases, Non Alcoholic Fatty Liver Disease (NAFLD), Non-Hodgkin Lymphoma, Non-Small Cell Lung Cancer, Osteoarthritis, Osteoporosis, Ovarian Cancer, Plaque Psoriasis (Psoriasis Vulgaris), Polycystic Kidney Disease, Post-Myocardial Infarction, Primary Progressive Multiple Sclerosis (PPMS), Prostate Cancer, Pulmonary Hypertension, Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome), Radiodermatitis, Relapsing Remitting Multiple Sclerosis (RRMS), Retinal Degeneration, Retinopathy, Subarachnoid Hemorrhage and Ulcerative Colitis.


Universities and Organizations that have studied Protandim:

  • Ohio State University
  • Louisiana State University
  • University of Kentucky
  • Harvard University
  • American Heart Association
  • National Institute of Health
  • University of Louisville
  • Colorado State University
  • Virginia Commonwealth University
  • University of Florida
  • University of Colorado
  • Texas Tech University
  • Universite de Montreal
  • National Institute on Aging
  • VU University Medical Center
  • Medical College of Wisconsin
  • University of Texas
  • China School of Pharmacy